Manufactured by Eli Lilly and Company and sold worldwide, baclofen is a prescription medication used to treat skeletal muscle spasticity and muscle spasms. It is commonly used to treat muscle stiffness, tension, and rigidity in adults and children.
Baclofen can also be used to treat and reduce the pain and inflammation associated with multiple sclerosis (MS). This includes reducing the risk of disability and promoting recovery in people with MS.
The FDA approved baclofen in 2010 for treating skeletal muscle spasticity in patients with MS. It is also used to treat pain associated with MS, such as stiffness and pain in muscles.
Baclofen is not approved for treating other conditions, such as depression and Parkinson's disease.
For more information about baclofen and its use in MS, see the
Baclofen is a skeletal muscle relaxant that can be prescribed for muscle stiffness and spasticity associated with MS. It works by increasing muscle relaxation, which helps to decrease pain and inflammation.
Oral baclofen tablets are made by Eli Lilly and Company and are used to treat muscle stiffness and pain associated with MS.
Baclofen Tablets are a prescription medication that has been approved by the FDA for treating skeletal muscle spasticity in adults and children, and is also used to treat pain associated with MS.
Baclofen Tablets are available in a variety of strengths, including:
Baclofen is also available in an oral suspension form, which is similar to an injectable form of baclofen. This form allows for dosing and dosing schedule in a safe and convenient manner.
Baclofen Tablets are available as a suspension form of baclofen that can be easily stored at room temperature and be taken without water. The suspension form is easy to transport and can be conveniently packaged for a variety of conditions, including:
The FDA approved baclofen in 2010 for treating muscle stiffness and pain in adults and children with MS.
The study was supported by the University of Oxford and the Department of Pharmacology, University of Oxford.
The study was conducted in compliance with the ethical guidelines of the University of Oxford's Declaration of Helsinki. Informed consent was obtained from all patients in accordance with the relevant guidelines and procedures. The study was approved by the Oxford Research Ethics Committee (No. 0.04.04.05-2) and the Ethics Committee for the study (ECF-04-08-20). All participants gave their informed consent.
The study was approved by the Ethics Committee for the study (ECF-04-08-20).
The drug, baclofen 10 mg, was administered orally once daily, in three treatment-experienced patients at three different sites over a 6-month period, at the beginning of the study and every 3 months thereafter. Each of the patients received at least 2 g baclofen (equivalent to the maximum daily dose of 10 mg) and was provided with a daily intake of 100 mg baclofen. The patients also received a high-fat meal (12 h before study entry). The patients were divided into two groups (n=6 per group). Group 1 received baclofen 10 mg, and the second group received a high-fat meal.
All patients in the baclofen 10 mg group were followed up for 3 months, during which they were evaluated by a blinded physician. The dose of baclofen 10 mg was gradually increased to 10 mg every 3 months over this period. The dose was then gradually decreased to the lowest possible dose (10 mg daily) to prevent exacerbation of the disease. The patients were advised to take oral baclofen at least 3 days before the study entry, and to take an additional drug regimen for 3 days every 4 weeks during the study. The patients were instructed to take this drug as soon as they felt their symptoms were sufficiently alleviated, and to resume their usual dosage after the first 4 weeks of treatment. The dose of baclofen 10 mg was increased to 100 mg every 4 weeks during the study period, but the maximum dose of baclofen was then adjusted to the lowest possible dose (10 mg daily) in order to prevent exacerbation. The dose of baclofen 10 mg was subsequently decreased to the lowest possible dose (100 mg every 4 weeks) in order to prevent exacerbation. The patient received a second dose of baclofen 10 mg every 4 weeks. The dose of baclofen 10 mg was gradually decreased to 100 mg every 4 weeks, during which the patient reported improved tolerability.
In addition to the above treatment-experienced patient groups, the patients in the baclofen 10 mg group were also evaluated at a single time point, in order to compare the clinical efficacy and tolerability of the treatment with baclofen 10 mg. These were all recruited into the study by a second study team (S. R. M.) who took part in the treatment of severe, and potentially life-threatening muscle spasticity in the patients included in the study.
The study was approved by the Oxford Research Ethics Committee (0.04.04.05-2).
The study was approved by the Oxford Research Ethics Committee (0.04.04.05-2) and the Ethics Committee for the study (ECF-04-08-20).
All patients gave their informed consent.
© 2016 The Netherlands Pharmacology SocietyAuthors: Paul J. Hamer, DVM, FAO, BNF, MRC, RAS, BMSThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License () which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Baclofen was developed for the treatment of muscle spasticity in patients with multiple sclerosis and as a prophylactic agent for severe spinal spasticity. It has shown great promise in the treatment of severe spasticity with marked improvement in spasticity.
Baclofen is an antispasmodic medication, used to treat muscle spasms caused by various conditions, including:
Baclofen is the brand name of baclofen. It is available in tablet and capsule form. Baclofen is a prescription medication and should only be used under the guidance of a healthcare professional. Baclofen may cause side effects such as headache, muscle pain, flushing, stomach upset, dizziness, and upset stomach. These side effects usually go away on their own within a few days and may go away with time. However, you may still experience some discomfort and swelling due to the use of this medication. If these side effects become bothersome or long-lasting, speak to your doctor or pharmacist for advice before taking this medication. Do not stop using this medication without first consulting your doctor.
The most common side effects of Baclofen include:
If any of these side effects get bothersome or do not go away, speak to your doctor. Your doctor may increase your dose to address the side effects.
Although Baclofen is a prescription medication, it is not known how many potential side effects occur. If you experience any of the following serious side effects, get medical attention immediately:
Baclofen may also cause dizziness or drowsiness. Avoid driving or operating heavy machinery while on this medication. Baclofen is not a controlled substance and is not intended to cure any underlying medical conditions or health problems you may have. Always consult your doctor before starting or stopping any medication, including Baclofen.
Baclofen is a medication used to manage multiple neurological disorders, including spasticity and spinal cord injuries. It works by reducing the activity of muscle spasticity and providing relief from muscle stiffness and tension, thereby alleviating symptoms of various neurological conditions. Baclofen is available in two forms: tablets and oral suspension.
Baclofen is typically taken once daily, starting from the first dose and gradually increasing the dose over several days. The most common side effects of Baclofen include muscle aches, headaches, and nervousness. Baclofen may also cause sedation and increased heart rate. It’s important to note that these effects are temporary and should be taken as directed.
Common side effects of Baclofen include muscle aches, headache, nausea, and dry mouth. These side effects usually improve within a few days. If you experience any severe or persistent side effects, you should consult your doctor.
Your doctor may start you with a lower dose, increasing it slowly over a few days to ensure maximum benefit. It is important to take the medication as prescribed, as it can cause side effects like headache, dizziness, and fatigue. It’s important to note that the dosage will depend on the individual and should not be adjusted without consulting a doctor.
To minimize the risk of side effects, follow these instructions:
To help prevent side effects, avoid alcohol, certain drugs, or certain foods. Avoid driving or operating machinery until you know how this medication affects you.
If you forget to take a dose, take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for the missed dose.
Store the medication in a cool and dry place away from direct sunlight. Keep out of reach of children.
Baclofen may interact with some medications. Inform your doctor if you’re taking any of the following:
You should discuss any questions or concerns with your doctor before starting baclofen.
Baclofen Tablets 20 mg by Teva is a muscle relaxer and an antispastic agent. Baclofen is used to treat muscle symptoms caused by multiple sclerosis, including spasm, pain, and stiffness. Baclofen may also be used for purposes not listed in this medication guide.
Each tablet, for oral administration, contains 20 mg baclofen. In addition, each tablet contains the following inactive ingredients: microcrystalline cellulose, pregelatinized starch, colloidal silicon dioxide, and magnesium stearate.
Baclofen tablets are useful for the alleviation of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity.
Patients should have reversible spasticity so that baclofen treatment will aid in restoring residual function. Baclofen may also be of some value in patients with spinal cord injuries and other spinal cord diseases.
Baclofen tablets are not indicated in the treatment of skeletal muscle spasm resulting from rheumatic disorders.
The efficacy of baclofen in stroke, cerebral palsy, and Parkinson’s disease has not been established and, therefore, it is not recommended for these conditions.
Brand: Teva Pharmaceuticals
Size: 1000 Tablets / Month
Size: 1500 Tablets / Year
* The product images are based on the images available on this page and are for reference only. It is important to consult your physician or pharmacist for more information.
BrittanyBaclofen tablets 20 mg by Teva are used to relieve signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity.
Baclofen tablets 20 mg by Teva may also be used for purposes not listed in this medication guide.
Baclofen tablets 20 mg by Teva are useful for the treatment of pain, clonus, and muscular rigidity caused by multiple sclerosis.
Baclofen tablets may also be of some use in patients with spinal cord injuries.
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